The SoClean uses ozone to sanitize whereas The Lumin uses a powerful UltraViolet-C light to disinfect. The SoClean must be purchased with an adapter to filter ozone through the CPAP machine and accessories can go into the chamber. The Lumin does not have any attachments but only kills surfaces that are exposed to the light within the sliding compartment. It is upto personal preference as they are both effective at sanitizing.